What is Tirzepatide (Mounjaro)?

Tirzepatide (brand name: Mounjaro) is a dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist used for the management of type 2 diabetes. It helps improve blood sugar control by enhancing insulin secretion, reducing glucagon release, and slowing digestion. Tirzepatide is also being studied for weight management and other metabolic conditions.

Tirzepatide is administered as a subcutaneous injection, typically once weekly.

• Generic name: tirzepatide
• Brand name: Mounjaro
• Drug classes: GIP and GLP-1 receptor agonists, antidiabetics

Warnings

• Do not use tirzepatide if you have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).
• Inform your doctor if you have a history of pancreatitis or gallbladder issues, as tirzepatide may increase the risk of these conditions.
• Tirzepatide is not intended for individuals with type 1 diabetes or diabetic ketoacidosis.
• Avoid using tirzepatide during pregnancy unless explicitly directed by your healthcare provider.

Before Using This Product

• Inform your healthcare provider if you have a history of kidney or liver disease, gastrointestinal disorders, or other metabolic conditions.
• Disclose all medications you are currently taking, including insulin or oral antidiabetic drugs, to avoid potential interactions.
• Ensure you understand proper injection techniques and storage requirements for tirzepatide.

How Should I Take Tirzepatide (Mounjaro)?

• Dosage: Tirzepatide is typically initiated at a low dose (2.5 mg once weekly) and gradually increased to a maintenance dose (up to 15 mg) based on your response and tolerability.
• Timing: Administer tirzepatide on the same day each week, with or without food, at any time of day.
• Administration: Inject tirzepatide under the skin of the abdomen, thigh, or upper arm. Rotate injection sites to minimize irritation.

What Happens If I Miss a Dose?

• If you miss a dose, take it as soon as you remember, as long as it is within 4 days of the missed dose.
• If more than 4 days have passed, skip the missed dose and continue with your regular schedule.
• Do not take two doses at the same time to make up for a missed dose.

What Happens If I Overdose?

• Symptoms of overdose may include severe nausea, vomiting, or low blood sugar (hypoglycemia).
• Seek emergency medical attention if you suspect an overdose.

What to Avoid

• Avoid excessive alcohol consumption, as it can increase the risk of hypoglycemia or gastrointestinal side effects.
• Avoid sharing injection pens, even if the needle is changed, to prevent the spread of infections.
• Avoid sudden changes in your diet or activity level without consulting your doctor, as these may impact blood sugar control.

Tirzepatide Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Decreased appetite
• Abdominal pain
• Vomiting

Seek immediate medical attention if you experience severe or unusual symptoms, such as:

• Severe abdominal pain (may indicate pancreatitis)
• Persistent vomiting or dehydration
• Signs of a serious allergic reaction, such as swelling of the face, lips, or tongue
• Vision changes or severe dizziness