What is PT-141?

PT-141, also known as bremelanotide, is a peptide medication used for the treatment of sexual dysfunction, including hypoactive sexual desire disorder (HSDD) in premenopausal women. Unlike other medications that target blood flow, PT-141 works directly on the central nervous system to enhance sexual arousal and desire.

PT-141 is available as a subcutaneous injection and is often used under medical supervision.

• Generic name: bremelanotide
• Brand name: Vyleesi
• Drug classes: Melanocortin receptor agonists

Warnings

• PT-141 should not be used by individuals with uncontrolled high blood pressure or cardiovascular conditions.
• Do not use PT-141 more than 8 times per month to avoid potential side effects.
• PT-141 may cause nausea in some users, particularly after the first dose.
• Pregnant or breastfeeding individuals should not use PT-141, as its safety in these populations has not been established.

Before Using This Product

• Inform your doctor if you have a history of high blood pressure, cardiovascular disease, or other medical conditions.
• Disclose any medications you are currently taking, especially those for hypertension or erectile dysfunction, as they may interact with PT-141.
• Do not use PT-141 if you are allergic to bremelanotide or any of its components.

How Should I Take PT-141?

• Dosage: PT-141 is typically administered as a 1.75 mg subcutaneous injection in the abdomen or thigh at least 45 minutes before sexual activity.
• Frequency: Do not use PT-141 more than once in 24 hours or more than 8 times per month.
• Administration: Follow the instructions provided by your healthcare provider or the medication guide carefully.

What Happens If I Miss a Dose?

• PT-141 is used as needed and does not have a regular dosing schedule. Missing a dose is unlikely.

What Happens If I Overdose?

• Symptoms of overdose may include severe nausea, vomiting, or increased blood pressure.
• Seek emergency medical attention if you suspect an overdose.

What to Avoid

• Avoid using PT-141 if you have consumed alcohol or other substances that may interact with the medication.
• Avoid self-administering higher doses than prescribed to prevent serious side effects.

PT-141 Side Effects

Common side effects may include:

• Nausea
• Flushing
• Headache
• Injection site reactions
• Increased blood pressure

Seek immediate medical attention if you experience severe or unusual symptoms, such as:

• Severe allergic reactions, such as swelling of the face, lips, or tongue
• Chest pain or shortness of breath
• Persistently high blood pressure