Ovulation Induction is a fertility treatment designed to stimulate the ovaries to produce and release eggs, enabling women who have irregular or absent ovulation to increase their chances of conception. This treatment involves using medications to regulate or stimulate ovulation, especially in women experiencing ovulatory dysfunction, a common cause of infertility. Ovulation-inducing medications include Clomid (clomiphene) and Ovidrel (human chorionic gonadotropin or hCG). These drugs work by targeting hormones that regulate the ovulation process, often by encouraging the development and release of a mature egg.

The medications for ovulation induction vary in their mechanism of action. Clomid and other clomiphene-based drugs are often first-line treatments that stimulate the release of hormones necessary for ovulation, typically administered in oral form. Other medications, like hCG injections (Pregnyl, Ovidrel), are used to trigger the final maturation and release of the egg. Injectable hormones, such as menotropins and recombinant follicle-stimulating hormones (FSH), directly stimulate the ovaries to produce multiple follicles, potentially increasing the chances of conception.

While these medications are generally safe, they carry risks, such as ovarian hyperstimulation syndrome (OHSS), which may lead to bloating, abdominal pain, and, in rare cases, severe complications. Another risk is the increased likelihood of multiple pregnancies. Ovulation induction is usually monitored through blood tests and ultrasound scans to track follicle development and hormone levels, ensuring safe and effective outcomes. Due to the complexity of ovulation and the potential risks, ovulation induction should only be pursued under the guidance of a fertility specialist.

Dosage for Ovulation Induction Treatment

• Clomid (Clomiphene Citrate): Typically, treatment starts with 50 mg per day for five days, beginning on the third, fourth, or fifth day of the menstrual cycle. If ovulation does not occur, the dose may be increased to 100 mg per day in subsequent cycles.
• Human Chorionic Gonadotropin (hCG): Given as a single injection of 5,000–10,000 IU after follicle maturation to trigger ovulation. This is often timed to occur 24-48 hours before planned intercourse or intrauterine insemination (IUI).

These doses are approximate and must be personalized by a healthcare provider to optimize effectiveness and reduce potential side effects.